【學(xué)術(shù)報(bào)告】Resorcinarene-based?Host?Molecules?Functionalized?with?Amino?Acids?and?Used?for?Separations
日期：2024-05-03
閱讀：2224
主題：Resorcinarene-based?Host?Molecules?Functionalized?with?Amino?Acids?and?Used?for?Separations
報(bào)告人：Roger?Harrison
時間：2024年5月3日（周五）10：00-11：30
地點(diǎn)：霞光樓220
邀請人：顏徐州，研究員
個人簡介
Professor?Roger?Harrison?received?his?PhD?from?the?University?of?Utah?in?1993?after?doing?organometallic?research?with?Thomas?Richmond.?Afterwards?he?did?post-doctoral?bioinorganic?research?with?Lawrence?Que?at?the?University?of?Minnesota.?In?1995?he?accepted?a?faculty?position?at?Brigham?Young?University?in?the?Department?of?Chemistry?and?Biochemistry?and?is?now?a?full?professor?there.?He?has?mentored?graduate?students?and?over?one?hundred?undergraduate?students.?His?research?group?focuses?on?using?resorcinarenes?for?the?separation?of?water?contaminants?and?synthesizing?zinc?oxide?and?magnetite?nanomaterials.
報(bào)告摘要
Resorcinarenes?have?a?rich?history?of?molecular?recognition.?Their?cavities?can?be?elongated?and?are?known?to?bind?guest?molecules.?The?ability?of?resorcinarenes?to?have?different?functional?groups?makes?them?good?candidates?to?be?used?for?selective?binding.?In?the?past?we?have?synthesized?resorcinarenes?with?metal?chelating?ligands.1,2?We?have?now?turned?our?focus?to?chiral?resorcinarenes?with?amino?acids.?One?of?these?new?resorcinarenes?has?alanine?and?binds?aromatic?amines?and?separates?metal?ions.3?Our?most?recent?resorcinarenes?contain?amino?acids?like?glutamic?acid?(Figure?1)?and?have?shown?the?ability?to?separate?water?contaminants?such?as?pharmaceuticals?and?polyfluoroalkyl?substances?(PFAS).4,5?As?more?medications?are?put?into?wastewater?by?our?growing?population,?more?of?these?drugs?are?ending?up?in?drinking?water.?The?quantification,?which?relies?on?the?separation?of?these?contaminants?of?emerging?concern,?is?facilitated?by?resorcinarenes?when?they?are?used?as?packing?materials?in?ion?chromatography?(IC).?The?synthesis?of?resorcinarenes?with?amino?acids?and?their?separations?of?water?contaminants?will?be?presented.?
