辦公電話:021-54742664
電子郵件:[email protected]
通訊地址:上海市東川路800號化學化工學院A樓525室
1995-1999:哈爾濱工業(yè)大學理學院,學士
1999-2001:哈爾濱工業(yè)大學理學院,碩士
2001-2005:上海交通大學化學化工學院,博士
2013:伊利諾伊大學厄巴納-香檳分校,高級訪問學者
2005-2006:上海交通大學化學化工學院,講師
2006-2010:上海交通大學化學化工學院,副教授
2010-至今:上海交通大學化學化工學院,教授
2008年11月:被遴選為上海交通大學高分子化學與物理專業(yè)博士生導師
2005年-至今:上海交通大學金屬基復合材料國家重點實驗室固定研究人員
1、超分子自組裝
2、嵌段共聚物的分子設(shè)計與可控合成
3、細胞仿生自組裝
主持國家杰出青年基金、973計劃項目課題、自然科學基金、教育部新世紀優(yōu)秀人才支持計劃、霍英東基金、全國百篇優(yōu)秀博士學位論文基金、上海市科技啟明星等多項課題研究。
論文
(1) Liu, Y.; Yu, C. Y.; Jin, H. B.; Jiang, B. B.; Zhu, X. Y.; Zhou, Y. F.*; Lu, Z. Y.*; Yan, D. Y., A Supramolecular Janus Hyperbranched Polymer and Its Photoresponsive Self-Assembly of Vesicles with Narrow Size Distribution, J. Am. Chem. Soc. 2013, 135, 4765.
(2) Dong, R. J.; Zhu, B. S.; Zhou, Y. F.*; Yan, D.Y.; Zhu, X.Y.*, Reversible photoisomerization of azobenzene containing polymeric systems driven by visible light, Polym. Chem. 2013, 4, 912.
(3) Wang, Y. L.; Li, B.; Zhou, Y. F.*; Lu, Z. Y.*, Yan, D.Y., Dissipative Particle Dynamics Simulation Study on the Mechanisms of Self-Assembly of Large Multimolecular Micelles from Amphiphilic Dendritic Multiarm Copolymers, Soft matter 2013, 9, 3293.
(4) Liu,Y.; Gao, Y.; Lu, Q. H.; Zhou, Y. F.*; Yan, D. Y., Bio-inspired hierarchical self-assembly of nanotubes into multidimensional and multi-scale structures, Nanoscale 2012, 4, 224.
(5) Tao, W.; Liu, Y.; Jiang, B. B.; Yu, S. R.; Huang, W.; Zhou, Y. F.*; Yan, D.Y.; A Linear-Hyperbranched Supramolecular Amphiphile and Its Self-Assembly into Vesicles with Great Ductility, J. Am. Chem. Soc. 2012, 134, 762.
(6) Dong, R. J.; Zhu, B. S.; Zhou, Y. F.*; Yan, D. Y.; Zhu, X. Y.*, “Breathing” Vesicles with Jellyfish-like On-Off Switchable Fluorescence Behavior, Angew. Chem. Int. Ed. 2012, 51, 11633.
(7) Jin, H. B.; Liu, Y.; Zheng, Y. L.; Huang, W.; Zhou, Y. F.*; Yan, D.Y., Cytomimetic Large-Scale Vesicle Aggregation and Fusion Based on Host-Guest Interaction, Langmuir 2012, 28, 2066.
(8) Jiang, B. B.; Tao, W.; Lu, X.; Liu, Y.; Jin, H. B.; Pang, Y.; Sun, X. Y. *; Yan, D. Y.; Zhou, Y. F.*, A POSS-Based Supramolecular Amphiphile and Its Hierarchical Self-Assembly Behaviors, Macromol. Rapid Commun. 2012, 33, 767.
(9) Jin, H. B.; Huang, w.; Zheng, Y. L.; Zhou, Y. F.*; Yan, D. Y., Construction of Macroscopic Cytomimetic Vesicle Aggregates Based on Click Chemistry: Controllable Vesicle Fusion and Phase Separation, Chem. Eur. J. 2012, 18, 8641.
(10) Jin, H. B.; Huang, w.; Zhu, X. Y.; Zhou, Y. F.*; Yan, D. Y., Biocompatible or biodegradable hyperbranched polymers: from self-assembly to cytomimetic applications, Chem. Soc. Rev. 2012, 41, 5986.
(11) Liu,Y.; Jin, H. B.; Zhu, S. M.; Liu, Y. C.*; Long, M. C.*; Zhou, Y. F.*; Yan, D. Y., A facile method for fabricating TiO2@mesoporous carbon and three-layered nanocomposites, Nanotechnology 2012, 23, 325602
(12) Yu, S. R.; Chen, J. X.; Dong, R. J.; Su, Y.; Ji, B.*; Zhou, Y. F.*; Zhu, X. Y.*; Yan, D. Y., Enhanced Gene Transfection Efficiency of PDMAEMA by Incorporating Hydrophobic Hyperbranched Polymer Cores: Effect of Degree of Branching, Polym. Chem. 2012, 3, 3324.
(13) Jin, H. B.; Zheng, Y. L.; Liu, Y.; Cheng, H. X.; Zhou, Y. F.*; Yan, D.Y., Reversible and Large-Scale Cytomimetic Vesicle Aggregation Based on Light-Responsive Host-Guest Interactions, Angew. Chem. Int. Ed. 2011, 50, 10352.
(14) Liu, J.Y.; Huang, W.*; Pang, Y.; Huang, P.; Zhu, X.Y.; Zhou, Y. F.; Yan, D.Y.*, Molecular Self-Assembly of A Homopolymer: An Alternative to Fabricate Drug Delivery Platform for Cancer Therapy, Angew. Chem. Int. Ed. 2011, 50, 9162.
(15) Zhu, X.Y.; Zhou, Y. F.*; Yan, D. Y.* Influence of Branching Architecture on Polymer Properties, J. Polym. Sci., Part B: Polym. Phys 2011, 49, 1277.
(16) Dong, R. J.; Liu, Y.; Zhou, Y. F.*; Yan, D.Y.; Zhu, X. Y.*, Photo-Reversible Supramolecular Hyperbranched Polymer Based on Host-Guest Interactions, Polym. Chem. 2011, 2, 2771.
(17) Cheng; H. X.; Deng; H.; Zhou; L. Z.; Su; Y.; Yu; S. R.; Zhu; X. Y.; Zhou, Y. F.*; Yan, D. Y., Improvement of gene delivery of PDMAEMA by incorporating a hyperbranched polymer core, J. Control. Release 2011, 152, E187.
(18) Liu, J.Y.; Pang, Y.; Huang, W.*; Zhu, Z. Y.; Zhu, X. Y.; Zhou, Y. F.; Yan, D.Y.*, Redox-Responsive Polyphosphate Nanosized Assemblies: A Smart Drug Delivery Platform for Cancer Therapy, Biomacromolecules 2011, 12, 2407.
(19) Liu, J.Y.; Pang, Y.; Huang, W.*; Huang, X.H.; Meng, L. L.; Zhu, X. Y.; Zhou, Y. F.; Yan, D.Y.*, Bioreducible Micelles Self-Assembled from Amphiphilic Hyperbranched Multiarm Copolymer for Glutathione-Mediated Intracellular Drug Delivery, Biomacromolecules 2011, 12, 1567.
(20) Dong, W.Y.; Cheng, H.X.; Yao, Y.A.; Zhou, Y. F.; Tong, G.S.; Yan, D.Y.; Lai, Y.J.; Li, W., Bioinspired Synthesis of Calcium Carbonate Hollow Spheres with a Nacre-Type Laminated Microstructure, Langmuir 2011, 27, 366.
(21) Cheng, H. X.; Yuan, X.J.; Sun, X.Y.; Li, K.P.; Zhou, Y. F.*; Yan, D. Y.*, Effect of Degree of Branching on the Self-Assembly of Amphiphilic Hyperbranched Multiarm Copolymers,Macromolecules 2010, 43, 1143.
(22) Wang, R.B.; Zhou, L. Z.; Zhou, Y. F.; Li, G. L.; Zhu, X. Y.*; Gu, H. C.; Jiang, X. L.; Li, H. Q.; Wu, J. l.; He, L.; Guo, X. Q.; Zhu, B. S.; Yan, D. Y., Synthesis and Gene Delivery of Poly(amido amine)s with Different Branched Architecture, Biomacromolecules 2010, 11, 489.
(23) Cheng, H. X.; Xie, S. A.; Zhou, Y. F.*; Huang, W.; Yan, D. Y.; Yang, J.T.; Ji, B. Effect of Degree of Branching on the Thermoresponsive Phase Transition Behaviors of Hyperbranched Multiarm Copolymers: Comparison of Systems with LCST Transition Based on Coil-to-Globule Transition or Hydrophilic-Hydrophobic Balance, J. Phys. Chem. B 2010, 114, 6291.
(24) Guo, B.; Sun X.Y.; Zhou, Y. F.*; Yan, D. Y.*, Supramolecular self-assembly and controllable drug release of thermosensitive hyperbranched multiarm copolymers, Sci. China Ser. B-Chem. 2010, 53, 487.
(25) Zhai, S.; Hong, H. Y.; Zhou, Y. F.*; Yan, D. Y.*, Synthesis of cationic hyperbranched multiarm copolymer and its application in self-reducing and stabilizing gold nanoparticles, Sci. China Ser. B-Chem. 2010, 53, 1114.
(26) Sun, X. Y.; Zhou, Y. F.*; Yan, D. Y., Rendering Hyperbranched Polyglycerol Adjustably Thermoresponsive by Adamantyl Modification and Host/Guest Interaction, Macromol. Chem. Phys. 2010, 211, 1940.
(27) Sun, X. Y.; Huang, W.; Zhou, Y. F.*; Yan, D. Y., Facile Fabrication of Narrowly-Distributed Polymeric Micelles via Host-Guest Inclusion Complexation of Hyperbranched Polymers and Cyclodextrin and its Two-Dimensional Self-assembly, Phys. Chem. Chem. Phys. 2010, 12, 11948.
(28) Zheng, Y. L.; Zhong, L.; Huang, W.; Zhou, Y. F.*; Yan, D. Y., “Flocculation-Resistant Multimolecular Micelles with Thermo-Responsive Corona from Dendritic Heteroarm Star Copolymers”, J. Polym. Sci., Part A: Polym. Chem. 2010, 48, 4428.
(29) Jin, H. B.; Zhou, Y. F.*; Huang, W.; Yan, D. Y., “Polymerization-like Multilevel Hierarchical Self-Assembly of Polymer Vesicles into Macroscopic Superstructures with Controlled Complexity”, Langmuir 2010, 26, 14512.
(30) Zhou, Y. F.; Huang, W.; Liu, J. Y.; Zhu, X. Y.*; Yan, D. Y.*, Self-Assembly of Hyperbranched Polymers and Its Biomedical Applications, Adv. Mater. 2010, 22, 4567.
(31) Liu, J. Y.; Pang, Y.; Huang, W.*; Zhai, X.; Zhu, X. Y.; Zhou, Y. F.; Yan, D. Y.*, Controlled Topological Structure of Copolyphosphates by Adjusting Pendant Groups of Cyclic Phosphate Monomers, Macromolecules 2010, 43, 8416.
(32) Liu, J.Y.; Huang, W.*; Pang, Y.; Zhu, X.Y.; Zhou, Y. F.; Yan, D.Y.*, Self-Assembled Micelles from an Amphiphilic Hyperbranched Copolymer with Polyphosphate Arms for Drug Delivery, Langmuir 2010, 26, 10585.
(33) Liu, J.Y.; Huang, W.*; Pang, Y.; Zhu, X. Y.; Zhou, Y. F.; Yan, D.Y.*, The in vitro biocompatibility of self-assembled hyperbranched copolyphosphate nanocarriers, Biomaterials 2010, 31, 5643.
(34) Liu, J.Y.; Pang, Y.; Huang, W.*; Zhu, X.Y.; Zhou, Y. F.; Yan, D.Y.*, Hyperbranched Polyphosphates for Drug Delivery Application: Design, Synthesis, and In Vitro Evaluation, Biomacromolecules 2010, 11, 1564.
(35) Liu, J.Y., Pang, Y.; Huang, W.; Zhu, X.Y., Zhou, Y. F.; Yan, D.Y., Self-Assembly of phospholipid-analogous hyperbranched polymers nanomicelles for drug delivery, Biomaterials 2010, 31, 1334.
(36) Dong, W. Y.; Zhou, Y. F.; Yan, D. Y.*; Mai, Y. Y.; He, L.; Jin, C., Honeycomb-Structured Microporous Films Made from Hyperbranched Polymers by the Breath Figure Method, Langmuir 2009, 25, 173.
(37) Zhou, Y. F.*; Yan, D. Y.*, Supramolecular self-assembly of amphiphilic hyperbranched polymers at all scales and dimensions: progress, characteristics and perspectives, Chem. Commun. 2009, 1172.
(38) Gao, Y.; Zhou, Y. F.*; Yan, D. Y.*, Preparation of polystyrene-grafted titanate nanotubes by in situ atom transfer radical polymerization, Sci. China Ser. B-Chem. 2009, 52, 344.
(39) Cheng, H. X.; Wang, S. G.; Yang, J. T.; Zhou, Y. F.*; Yan, D. Y. *, Synthesis and self-assembly of amphiphilic hyperbranched polyglycerols modified with palmitoyl chloride, J. Colloid Interface Sci. 2009, 337, 278.
(40) Guo, B.; Shi, Z. Q.; Yao, Y.; Zhou, Y. F.*; Yan, D. Y.*, Facile Preparation of Novel Peptosomes through Complex Self-Assembly of Hyperbranched Polyester and Polypeptide, Langmuir 2009, 25, 6622.
(41) Gao, Y.; Zhou, Y. F.*; Yan, D. Y.*, Temperature-sensitive and highly water-soluble titanate nanotubes, Polymer 2009, 50, 2572.
(42) Zhang, Y. W.; Huang, W.*; Zhou, Y. F.; Yan, D. Y.*, Complex Self-Assembly of Hyperbranched Polyamidoamine/Linear Polyacrylic Acid in Water and Their Functionalization, J. Phys. Chem. B 2009, 113, 7729.
(43) Sun, X. Y.; Zhou, Y. F.*; Yan, D. Y.*, Drug release property of a pH-responsive double-hydrophilic hyperbranched graft copolymer, Sci. China Ser. B-Chem. 2009, 52, 1703.
(44) Hong, H. Y.; Mai, Y. Y.; Zhou, Y. F.*; Yan, D. Y.*; Chen, Y., Synthesis and Supramolecular Self-Assembly of Thermosensitive Amphiphilic Star Copolymers Based on a Hyperbranched Polyether Core, J. Polym. Sci., Part A: Polym. Chem. 2008, 46, 668.
(45) Shi, Z. Q.; Zhou, Y. F.*; Yan, D. Y., Facile Fabrication of pH-Responsive and Size-Controllable Polymer Vesicles From a Commercially Available Hyperbranched Polyester”, Macromol. Rapid Commun. 2008, 29, 412.
(46) Zhong, L.; Zhou, Y. F.*; Yan, D. Y.*, Pan, C. Y., Synthesis of a Multi Alternating-Arm-Containing Dendritic Star Copolymer by RAFT and Cationic Ring-Opening Polymerization, Macromol. Rapid Commun. 2008, 29, 1385.
(47) Guo, Z.; Zhang, Y. W.; Huang, W.*; Zhou, Y. F.; Yan, D. Y., Terminal modification with 1-adamantylamine to endow hyperbranched polyamidoamine with thermo-/pH-responsive properties, Macromol. Rapid Commun. 2008, 29, 1746.
(48) Gao, Y.; Gao, X.; Zhou, Y. F.*; Yan, D. Y.*, Preparation of poly(methyl methacrylate) grafted titanate nanotubes by in situ atom transfer radical polymerization, Nanotechnology 2008, 19, 495604.
(49) Zhou, Y. F.; Yan, D. Y.*; Dong, W. Y.; Tian, Y., Temperature-Responsive Phase Transition of Polymer Vesicles: Real-Time Morphology Observation and Molecular Mechanism, J. Phys. Chem. B 2007, 111, 1262.
(50) Dong, W. Y.; Zhou, Y. F.*; Yan, D. Y.*; Li, H.; Liu, Y., pH-responsive self-assembly of carboxyl-terminated hyperbranched polymers, Phys. Chem. Chem. Phys. 2007, 9, 1255.
(51) Hong, H. Y.; Mai, Y. Y.; Zhou, Y. F.*; Yan, D. Y.*; Cui, J., Self-Assembly of Large Multimolecular Micelles from Hyperbranched Star Copolymers, Macromol. Rapid Commun. 2007, 28, 591.
(52) Zhang, Y. W.; Huang, W.*; Zhou, Y. F.; Yan, D. Y.*, A physical gel made from hyperbranched polymer gelator, Chem. Commun. 2007, 2587–2589.
(53) Mai, Y. Y.; Zhou, Y. F.*; Yan, D. Y.*, Real-Time Hierarchical Self-Assembly of Large Compound Vesicles from an Amphiphilic Hyperbranched Multiarm Copolymer, Small 2007, 3, 1170 – 1173.
(54) Shi, Z. Q.; Gao, X.; Song, D.; Zhou, Y. F.*; Yan, D. Y.*, Preparation of poly(?-caprolactone) grafted titanate nanotubes, Polymer 2007, 48, 7516
(55) Shi, Z. Q.; Zhou, Y. F.; Yan, D. Y.*, Preparation of robust poly(ε-caprolactone) hollow spheres with controlled biodegradability, Macromol. Rapid Commun. 2006, 27, 1265. (AUG)
(56) Shi, Z. Q.; Zhou, Y. F.; Yan, D. Y.*, Preparation of poly(beta-hydroxybutyrate) and poly(lactide) hollow spheres with controlled wall thickness, Polymer 2006, 47, 8073.
(57) Mai, Y. Y.; Zhou, Y. F.*; Yan, D. Y.*; Hou, J., Quantitative Dependence of Crystallinity on Degree of Branching for Hyperbranched Poly[3-ethyl-3-(hydroxymethyl)oxetane], New J. Phys. 2005, 7 (42).
(58) Zhou, Y. F.; Yan, D. Y.*, Real-Time Membrane Fission of Giant Polymer Vesicles, Angew. Chem. Int. Ed. 2005, 44, 3223.
(59) Huang, W.; Zhou, Y. F.; Yan, D. Y.*, Direct Synthesis of Amphiphilic Block Copolymers from Glycidyl Methacrylate and Poly(ethylene glycol) by Cationic Ring-Opening Polymerization and Supramolecular Self-Assembly Thereof, J. Polym. Sci., Part A: Polym. Chem. 2005, 43, 2038.
(60) Zhou, Y. F.; Yan, D. Y.*, Real-Time Membrane Fusion of Giant Polymer Vesicles, J. Am. Chem. Soc. 2005, 127, 10468.
(61) Mai, Y. Y.; Zhou, Y. F.*; Yan, D. Y.*, Synthesis and Size-Controllable Self-Assembly of A Novel Amphiphilic Hyperbranched Multi-Arm Copolyether, Macromolecules 2005, 38, 8679.
(62) Gong, W.; Mai, Y. Y.; Zhou, Y. F.; Qi, N.; Wang, B.*; Yan, D. Y.*, Effect of the degree of branching on atomic-scale free volume in hyperbranched poly[3-ethyl-3-(hydroxymethyl)oxetane], A positron study, Macromolecules 2005, 38, 9644
(63) Jia, Z. F.; Zhou, Y. F.; Yan, D. Y.*, Amphiphilic star-block copolymers based on a hyperbranched core: Synthesis and supramolecular self-assembly, J. Polym. Sci., Part A: Polym. Chem. 2005, 43, 6534.
(64) Zhou, Y. F.; Yan, D. Y.*, Supramolecular Self-Assembly of Giant Polymer Vesicles With Controlled Size, Angew. Chem. Int. Ed. 2004, 43, 4896.
(65) Yan, D. Y.; Zhou, Y. F.; Hou, J., Supramolecular Self-assembly of Macroscopic Tubes, Science, 2004, 303, 65..
9、邀請報告
Synthesis and self-assembly of hyperbranched-based supramolecular polymers. 3rd Chemical Science Symposium on Functional Supramolecular Materials. Hangzhou, June. 2013, Invited.
Hyperbranched-based supra-molecular polymers. SINO‐FRENCH WORSHOP Nanostructured polymers and nanohybrides:Towards properties and functions. Shanghai, June. 2013, Invited.
Hyperbranched-based supramolecular polymers. Australian Technology Network (ATN)/Shanghai Jiao Tong University Joint Research Workshop. Shanghai, April. 2013, Invited.
Hyperbranched-based supra-molecular polymers and their self-assembly behaviors. 1st China-Australia Polymer Mission. Shanghai, Janu. 2013, KeyNote.
Hyperbranched-based supra-molecular amphiphiles and their self-assembly behaviors. The 5th International Symposium on Polymer Chemistry. Changchun, China. June, 2012. Invited.
Cytomimetic chemistry based on hyperbranched polymer vesicles, 3rd Sino-French Bilateral Seminar on Macromolecules and Soft Matter. Hefei, China. Sep. 2012. Invited.
Stimuli-Responsive Hyperbranched Polymers and Their Self-Assemblies. The 94th Canadian Chemistry Conference and Exhibition (CSC2011), Montreal, Canada. June, 2011. Invited.
Self-Assembly of Hyperbranched Polymers and Its Biomedical Applications. Japan-China Joint Symposium on Functional Supramolecular Architectures. Changchun, China. July, 2010. Invited.
Self-Assembly of Hyperbranched Polymers and Its Biomedical Applications. The Second Sino-French Seminar at the ESPCI ParisTech, Paris, French. Oct. 2010. Invited.
Supramolecular Self-Assembly of Hyperbranched Polymers at All Scales and Dimensions. S-China Workshop for Early Career Chemical Scientists—SUPRAMOLECULAR CHEMISTRY. Beijing, China. Oct. 2009. Invited.
Supramolecular Self-Assembly of Hyperbranched Polymers at All Scales and Dimensions. The 6th International Dendrimer Symposium (IDS 6). Stockholm, Sweden. June, 2009. KeyNote.
1、2012年度 國家杰出青年基金
2、2009年度 國家自然科學二等獎(第二完成人)
3、2008年度 全國百篇優(yōu)秀博士學位論文獎
4、2007年度 上海市自然科學一等獎(第二完成人)
5、2007年度 入選教育部新世紀優(yōu)秀人才計劃
6、2006年度 入選上海市青年科技啟明星計劃
7、2006年度 獲中國化學會-約翰威立出版公司青年化學論文獎
1、本科生:《生物醫(yī)藥高分子》
2、研究生:《學術(shù)前沿進展》
地址:上海市東川路800號 200240
電話:021-54742893
E-mail:[email protected]